Our
Laboratory is investigating the mechanism by which HIV and other retroviruses
integrate a DNA copy of their genome into host DNA, an essential step in the
retroviral replication cycle. Current research focusses on the structure and
function of HIV integrase protein and the mechanism by which the cellular BAF
protein protects retroviral DNA from self-destructive autointegration into its
own DNA.
Department of Health and Human Services
Last updated February 6th, 2006
